Precursor lesions of malignant gastric cancer and associations with eating habits

Abstract

Introduction: Associations between dietary habits and precursor lesions of gastric malignancies including chronic atrophic gastritis, intestinal metaplasia and mild dysplasia were identified in men and women between the ages of 30 and 60 who came to the gastroenterology department of the Center for Research on Digestive Diseases of the city of Pasto, Nariño in the last quarter of 2015 and the first half of 2016. Methodology: This is a cross-sectional analytical study in which histological, social, demographic, anthropometric and dietary variables were analyzed. Descriptive, bivariate and multivariate analyzes were performed using crude and adjusted odds ratios with a 95% CI. Results: Of the 231 patients surveyed, 35.5% were diagnosed histologically with precursor lesions. The average age was 46 years old, and 57.1% of the cases were women, 32.5% were professionals, and 58% were affiliated with the subsidized health care scheme. These lesions were associated with cereal consumption of above 10 exchanges (OR 2.20, 95% CI: 1.08 - 4.47) and with and fat consumption above 8.5 exchanges (OR 2.52, 95% CI: 1.28-4.94). Adding salt to meals increased the likelihood of developing stomach lesions by 1.94 (95% CI: 1.03-3.66). Regular consumption of vegetables for more than two exchanges reduced the likelihood of stomach lesions (OR 0.53, 95% CI: 0.27-0.99). Conclusion: This study aims at contributing knowledge about factors that involved in initiation, promotion and progression of gastric cancer. © 2017 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología.